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Wednesday, August 14, 2013

Mouth bacteria may trigger bowel cancer

Mouth bacteria may trigger bowel cancer



Researchers say they have uncovered how bacteria may set off a chain reaction leading to bowel cancer.
Fusobacteria, commonly found in the mouth, cause overactive immune responses and turn on cancer growth genes, two US studies reveal.
The microbes had been linked with colorectal cancer before but it was not known whether they were directly involved in tumour growth.
Inside the mouth
The early findings are published in the journal Cell Host & Microbe.

In addition to potential new treatments, the discovery could lead to better early diagnosis and prevention, experts hope.
The first study, carried out by Harvard Medical School researchers, showed that fusobacteria were present in high numbers in adenomas - a benign bowel growth that can become cancerous over time.

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